Dysplasia vs. Hyperplasia: What’s the Difference?

Main Difference

The main difference between Dysplasia and Hyperplasia is that the Dysplasia is a abnormal development, at macroscopic or microscopical level and Hyperplasia is a increase in the amount of organic tissue that results from cell proliferation.

• Dysplasia

  Dysplasia (from Ancient Greek δυσ- dys-, “bad” or “difficult” and πλάσις plasis, “formation”) is a term used in pathology to refer to an abnormality of development or an epithelial anomaly of growth and differentiation (epithelial dysplasia).

  The terms hip dysplasia, fibrous dysplasia, and renal dysplasia refer to an abnormal development, at macroscopic or microscopical level.

  Myelodysplastic syndromes, or dysplasia of blood-forming cells, show increased numbers of immature cells in the bone marrow, and a decrease in mature, functional cells in the blood.

• Hyperplasia

  Hyperplasia (from ancient Greek ὑπέρ huper, “over” + πλάσις plasis, “formation”), or hypergenesis, is an increase in the amount of organic tissue that results from cell proliferation. It may lead to the gross enlargement of an organ, and the term is sometimes confused with benign neoplasia or benign tumor.

  Hyperplasia is a common preneoplastic response to stimulus. Microscopically, cells resemble normal cells but are increased in numbers. Sometimes cells may also be increased in size (hypertrophy). Hyperplasia is different from hypertrophy in that the adaptive cell change in hypertrophy is an increase in the size of cells, whereas hyperplasia involves an increase in the number of cells.

• Dysplasia (noun)

  Abnormal development of cells or tissue, often a precancerous stage of growth.

• Hyperplasia (noun)

  An increase in the size of a tissue or organ due to increased number of cells.

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