What is the Difference Between Clopidogrel Bisulfate and Clopidogrel Hydrogen Sulfate

The key difference between clopidogrel bisulfate and clopidogrel hydrogen sulfate is their treatment. Clopidogrel bisulfate is useful in treating the symptoms of acute coronary syndrome, including stroke, blood clots, and serious heart problems that follows a heart attack, severe chest pain, or circulation problems, whereas clopidogrel hydrogen sulfate is useful to prevent atherothrombotic events in adults.

Both clopidogrel bisulfate and clopidogrel hydrogen sulfate are closely similar to each other in appearance and use. But they are useful in different occasions of treatments.

CONTENTS

1. Overview and Key Difference
2. What is Clopidogrel Bisulfate 
3. What is Clopidogrel Hydrogen Sulfate
4. Similarities – Clopidogrel Bisulfate and Clopidogrel Hydrogen Sulfate
5. Clopidogrel Bisulfate vs Clopidogrel Hydrogen Sulfate in Tabular Form
6. Summary – Clopidogrel Bisulfate vs Clopidogrel Hydrogen Sulfate 

What is Clopidogrel Bisulfate?

Clopidogrel Bisulfate is a prescription medicine useful in treating the symptoms of acute coronary syndrome, including stroke, blood clot, and serious heart problems that comes following a heart attack, severe chest pain, or circulation problems. We can use this medication alone or with other medications. This medication belongs to a group of antiplatelet agents. However, it is not confirmed if Clopidogrel Bisulfate is suitable and effective for children.

Clopidogrel Bisulfate and Clopidogrel Hydrogen Sulfate - Side by Side Comparison

Figure 01: Synthesis of Clopidogrel Bisulfate

There can be some side effects, including pale skin, easy bruising, yellowing of the skin, fast heartbeats, shortness of breath, headache, fever, weakness, feeling of tiredness, etc.

The effectiveness of this medication comes from its antiplatelet activity. This activity depends on the conversion to an active metabolite by the cytochrome system.

What is Clopidogrel Hydrogen Bisulfate?

Clopidogrel Hydrogen Bisulfate is a medication that consists of the active substance clopidogrel. This medication is available in the market as pink-colored tablets. We can categorize it as a generic medicine, and it is similar to Clopidogrel Bisulfate.

Clopidogrel Bisulfate and Clopidogrel Hydrogen Sulfate - Side by Side Comparison

Clopidogrel Hydrogen Bisulfate is useful for adults to prevent atherothrombotic events. The type of patients this medication is given to patients who recently had a myocardial infarction, patients who recently had an ischaemic stroke, and patients having acute coronary syndrome.

This medication works as an inhibitor of platelet aggregation. Therefore, it helps to prevent blood clots from forming. It can stop aggregation by blocking a substance known as ADP from attaching to a special receptor on the surface.

What are the Similarities Between Clopidogrel Bisulfate and Clopidogrel Hydrogen Sulfate?

  • Clopidogrel bisulfate and clopidogrel hydrogen sulfate are available as pink-colored tablets.
  • Both are antiplatelet agents and prevent blood clots from forming.
  • What is the Difference Between Clopidogrel Bisulfate and Clopidogrel Hydrogen Sulfate?

    Both clopidogrel bisulfate and clopidogrel hydrogen sulfate are closely similar to each other in appearance, uses, etc. But they are useful in different occasions of treatments. The key difference between clopidogrel bisulfate and clopidogrel hydrogen sulfate is that clopidogrel bisulfate is useful in treating the symptoms of acute coronary syndrome, including strokes, blood clots, and serious heart problems that come following a heart attack, severe chest pain or circulation problems whereas clopidogrel hydrogen sulfate is useful for adults to prevent atherothrombotic events.

    The below infographic presents the differences between clopidogrel bisulfate and clopidogrel hydrogen sulfate in tabular form for side-by-side comparison.

    Summary – Clopidogrel Bisulfate vs Clopidogrel Hydrogen Sulfate

    Both clopidogrel bisulfate and clopidogrel hydrogen sulfate are antiplatelet drugs. The key difference between clopidogrel bisulfate and clopidogrel hydrogen sulfate is that clopidogrel bisulfate is useful in treating the symptoms of acute coronary syndrome including stroke, blood clots, and serious heart problems that comes following a heart attack, severe chest pain or circulation problems whereas clopidogrel hydrogen sulfate is useful for adults to prevent atherothrombotic events.

    Reference:

    1. “Plavix (Clopidogrel Bisulfate): Uses, Dosage, Side Effects, Interactions, Warning.” RxList, 11 Mar. 2021.
    2. “Clopidogrel Hydrogen Sulfate.” National Center for Biotechnology Information. PubChem Compound Database, U.S. National Library of Medicine.

    Image Courtesy:
    2. “Petal, finger, food, color, medicine, pink, baking, macaroon, dessert, lip, package, close up, colour, icing, pills, fondant, sweetness, tablets, medical, drugs, medication, cure” (CC0) via Pxhere

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